South Carolina Nonprofit Resource Guide
"Dum Spiro Spero" — The Palmetto State
About This Guide
This guide was created to help individuals and families in South Carolina navigate long-term care with more clarity and confidence. Whether you're planning ahead or facing an immediate care need, finding the right support can feel overwhelming.
Inside, you'll find a curated list of nonprofit organizations across South Carolina, including caregiver support services, disease-specific foundations, veteran resources, and community-based programs. Each listing includes verified contact information and a brief description to help you quickly understand what's available.
Our goal is to make it easier for you to explore your options, connect with trusted long-term care resources in South Carolina, and take the next step with confidence.
We strive to keep this directory accurate and up-to-date. However, nonprofit organizations change, merge, or close over time, and web addresses can change without notice. Always verify contact details directly with each organization. If you find an outdated listing or are a nonprofit that isn't listed and would like to be included, please reach out to us at hello@LTCareNav.com.
| Agency | Address / Phone | Counties Served |
|---|---|---|
| Central Midlands Council of Governments AAA centralmidlands.org | 236 Stoneridge Dr. Columbia, SC 29210 (803) 376-5390 | Fairfield, Lexington, Newberry, Richland (Columbia metro — state capital; University of SC; I-20/I-26 corridor) |
| Lower Savannah Council of Governments AAA lowersavannah.org | 3023 St. Matthews Rd. Orangeburg, SC 29118 (803) 536-6570 | Aiken, Allendale, Bamberg, Barnwell, Calhoun, Orangeburg (southwest SC — Aiken: nuclear and horse country; Savannah River Site; rural Black Belt communities with significant health disparities) |
| Santee-Lynches Regional Council of Governments AAA santeelynches.org | 36 W. Liberty St. Sumter, SC 29150 (803) 775-7381 | Clarendon, Kershaw, Lee, Sumter (central SC — Sumter, Shaw Air Force Base; rural communities; Lake Marion recreation area) |
| Waccamaw Regional Council of Governments AAA waccamawreg.org | 1230 Highmarket St. Georgetown, SC 29440 (843) 546-8502 | Georgetown, Horry, Williamsburg (northeastern SC coast — Myrtle Beach resort corridor; Georgetown rice plantation heritage; rural Williamsburg County) |
| Pee Dee Regional Council of Governments AAA peedeeregion.org | P.O. Box 5719 Florence, SC 29502 (843) 669-3138 | Chesterfield, Darlington, Dillon, Florence, Marion, Marlboro (Pee Dee region — Florence hub; rural tobacco and agricultural communities; NASCAR heritage; significant health disparities) |
| Lowcountry Council of Governments AAA lowcountrycog.org | P.O. Box 98 Yemassee, SC 29945 (843) 726-5536 | Beaufort, Colleton, Hampton, Jasper (Lowcountry SC — Hilton Head Island; Beaufort; Gullah-Geechee cultural heartland; Parris Island MCRD; rural Jasper and Hampton counties) |
| Berkeley-Charleston-Dorchester Council of Governments AAA bcdcog.com | 500 Faison Rd. Charleston, SC 29412 (843) 529-0400 | Berkeley, Charleston, Dorchester (Charleston metro — SC's largest metro; historic Charleston; Joint Base Charleston; rapidly growing tri-county region) |
| Upper Savannah Council of Governments AAA uppersavannah.org | 369 Fairview Dr. Greenwood, SC 29649 (864) 941-8090 | Abbeville, Edgefield, Greenwood, Laurens, McCormick, Saluda (upper Savannah River valley — Greenwood; rural Piedmont and Savannah River communities; Lakes Greenwood and Thurmond) |
| Appalachian Regional Commission / Appalachian COG AAA appalachianregionalsc.org | 30 Century Circle Greenville, SC 29607 (864) 242-9733 | Anderson, Cherokee, Greenville, Oconee, Pickens, Spartanburg, Union (Upstate SC — Greenville-Spartanburg metro; SC's fastest-growing region; BMW and Michelin manufacturing; Blue Ridge foothills; Cherokee County) |
| Catawba Regional Council of Governments AAA catawbaregional.org | 30 S. Herlong Ave. Rock Hill, SC 29732 (803) 327-9041 | Chester, Lancaster, Union, York (Catawba River valley — Rock Hill; Fort Mill; Charlotte, NC metro spillover; York County is SC's fastest-growing county) |
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